Redox-Enhanced Incretin Modulation
Mechanistic Synergy for Research:
- Glutathione (GSH) reduces systemic oxidative stress, which contributes to insulin resistance and mitochondrial dysfunction in obesity models.
- Together, NAD⁺ and GSH maintain redox homeostasis while supporting Semaglutide’s incretin-based glycemic regulation.
Combined Benefits:
- GSH reduces hepatic and adipose inflammation, complementing Semaglutide’s insulinotropic effects.
- NAD⁺ regenerates GSH via NADPH, maintaining antioxidant capacity during metabolic stress.
Use Cases:
Type 2 diabetes models, inflammatory metabolic syndromes, mitochondrial redox modulation.
