Mitochondrial Longevity & Antioxidant Protection Stack
Mechanistic Synergy for Research:
- NAD⁺ is a central metabolic cofactor required for ATP production, DNA repair (via PARPs), and longevity-associated sirtuin activation (SIRT1, SIRT3).
- Glutathione (GSH) is the body’s master antioxidant, preserving mitochondrial and cytosolic redox balance, detoxifying ROS, and protecting DNA/protein structures.
Combined Benefits:
- Energy + Defense: NAD⁺ supports mitochondrial biogenesis and cellular respiration; GSH prevents oxidative apoptosis and maintains redox homeostasis.
- DNA & Protein Integrity: Together, they reduce oxidative lesions, improve repair signaling, and maintain metabolic function in senescent-prone cells.
- Sirtuin-Powered Anti-Aging: NAD⁺-driven SIRT1 activity supports inflammation suppression, telomere preservation, and chromatin stability.
Use Cases:
Longevity research, oxidative stress studies, mitochondrial function and age-related metabolic decline models.








