Enhanced Regeneration with Copper-Driven ECM Remodeling
Mechanistic Synergy for Research:
This tri-peptide formulation expands the regenerative scope by integrating GHK-Cu, a copper-carrying tripeptide known for its role in tissue remodeling and anti-inflammatory gene expression.
- Expanded Extracellular Matrix (ECM) Remodeling:
GHK-Cu upregulates key ECM components such as collagen types I and III, elastin, and glycosaminoglycans. Paired with BPC-157’s pro-collagen effects and TB-500’s stimulation of fibroblasts, this trio provides a matrix-regenerative environment conducive to structural restoration. - Anti-fibrotic & Anti-inflammatory Synergy:
GHK-Cu modulates TGF-β1 expression, helping to prevent excessive scar formation while maintaining tissue elasticity. When combined with the inflammation-suppressing actions of BPC-157 and TB-500, the result is a highly balanced repair process with reduced fibrosis risk. - Angiogenic & Neurotrophic Amplification:
All three peptides promote angiogenesis and contribute to nerve regeneration: BPC-157 protects dopaminergic neurons, TB-500 supports axon outgrowth, and GHK-Cu stimulates NGF (nerve growth factor) production. - Copper-Dependent Enzymatic Support:
GHK-Cu provides bioavailable copper, essential for the activity of lysyl oxidase and superoxide dismutase—enzymes critical for collagen cross-linking and oxidative defense—thereby enhancing structural and redox integrity in regenerating tissues.
Best suited for:
Research models involving skin and connective tissue healing, nerve regeneration, and anti-fibrotic therapy.










